One True Thing
- Taon: 1998
- Bansa: United States of America
- Genre: Drama, Romance
- Studio: Universal Pictures, Monarch Pictures, Ufland
- Keyword: dysfunctional family, cancer, death of parent
- Direktor: Carl Franklin
- Cast: Meryl Streep, Renée Zellweger, William Hurt, Tom Everett Scott, Lauren Graham, Nicky Katt